The hypothalamus and pituitary gland are a single interconnected body system. The hypothalamic-pituitary system is responsible for the work of all endocrine glands. The hypothalamus is the highest regulator of the neuroendocrine system, located in the basal region of the brain. It participates in the regulation of the autonomic functions of the body, which are responsible for blood pressure, vascular permeability, heat regulation and heat transfer, appetite, metabolic processes, regulation of sleep and mental activity. The hypothalamus regulates the activity of the peripheral endocrine glands through the pituitary gland. Disruption of the hypothalamic-pituitary system affects all organs and tissues of our body.