Prostatitis is an inflammatory lesion of the prostate gland, which is the most common urological disease among men aged 20-50 years. The reasons for the development of the inflammatory process in the prostate can be very different. Much depends on the physiological characteristics of a particular organism and lifestyle. Often, prostatitis develops against the background of a genitourinary infection: chlamydia, fever, trichomoniasis, mycoplasmosis, ureaplasmosis and others. However, today it is known that the triggering mechanism for the development of the inflammatory process in the prostate gland is neuroendocrine and immune changes, in which metabolic processes are impaired and the protective functions of the body are weakened. Hypothermia is also a significant negative factor in the development of prostatitis, which leads to a decrease in local immunity.